Micky van de Ven Double Ends The Toffees' Unbeaten Streak at New Stadium
Micky van de Ven emerged as the first backline player to score twice in a Premier League game for Tottenham since the Belgian defender in spring 2013.
Match summary
Micky Van de Ven nods into the net twice in opening period
The home side's Jake O'Brien has goal ruled after VAR review
Pape Matar Sarr nets final goal in dying moments
The defeat is the Merseyside club's initial at their new ground
Micky van de Ven scored on two occasions as Spurs prolonged their winning streak in away games in the top division and delivered Everton their initial loss at Hill Dickinson Stadium.
The Toffees were undefeated in their five previous fixtures at their new ground at Bramley-Moore Dock, having departed their historic home behind after more than a century at the end of the previous campaign.
But Spurs captain the Dutchman pounced twice from corners in the first half to place their impressive record at jeopardy, and they were unable to mount a comeback before Pape Matar Sarr - set up by ex-Everton forward Richarlison - headed home a final goal to put the game to bed.
The Everton defender believed he had equalized the scores five minutes after Van de Ven's opener, glancing a bullet header past the Spurs keeper from an Everton corner.
Beto, meanwhile, failed to convert a number of opportunities, while Vicario made a series of fine stops to ensure Tottenham went five matches on the road without defeat in the English top flight.
But the VAR stepped in, advising the match official to review the score on the pitchside monitor and the official ruled that Jack Grealish and the attacker were in offside positions and had interfered with the Tottenham goalkeeper.
This victory elevates Thomas Frank's side up to third in the division, a handful of points off local foes and table-toppers the Gunners.
The Merseyside club remain in 14th position and sit six points ahead of the drop zone.
Spurs breakdown: Van de Ven excels in duties at each end of pitch
Following a drab midweek display in the European competition against the French side, where they mustered a mere two shots on target, Frank opted for Randal Kolo Muani in attack instead of ex-Everton forward the Brazilian.
The new arrival was failed to influence the game before being replaced for the substitute after an hour on the pitch, but it emerged he wasn't needed in the final outcome.
Centre-back Van de Ven transformed into an offensive threat to be feared.
Tottenham's first goal came from a well-worked set-piece play, with Rodrigo Bentancur heading the ball back across the six-yard box for an free the defender to head home.
And the captain - filling in as skipper in Cristian Romero's absence - notched his second in first-half stoppage time as he rose above Jordan Pickford to nod in.
Van de Ven was just as impressive in defensive duties, combining effectively with his defensive colleague as the pair dealt superbly with the 34 crosses sent their way by Everton.
Toffees breakdown: Toffees lacking finishing touch
Everton's recent stadium had been a fortress, but it seems the novelty may have worn off somewhat and supporters flocked to the gates after Sarr's third for Tottenham.
The break in the team's unbeaten home run will not be a massive worry for David Moyes, but their striker situation will be.
The forward and the other striker - the Everton's pair of recognised centre-forwards - had scored only a single goal combined before Sunday's outing.
And they were failed to add to that miserable record on a damp and dreary night on Merseyside.
The striker's performance was summed up when he opted to bicycle-kick a clear chance from near the goal, even with having space and opportunity to reposition for a more conventional attempt that would have challenged the keeper.
Barry, too, failed to make an impact after coming on for the starter in the 65th minute.
It was not for a lack of opportunity. Most of the home side's attacks came through the winger and Ndiaye, who tirelessly whipped threatening crosses into the Spurs box.
What next for these two sides?
Everton: The team head to Sunderland in the top flight on Monday, 3 November at 8 PM.
Spurs: The London club travel to St James' Park on Wednesday, 29 October for their next round Carabao Cup match against Newcastle.